Welcome to the 21c Museum Hotel

21c Museum Hotel is more than just a place to spend the night – it's a 90-room boutique hotel, contemporary art museum, award-winning restaurant and cultural civic center nestled in the heart of Museum Row in historic downtown Louisville. With over 5000 square feet of art-filled meeting and event space, 21c guests enjoy authentic Southern hospitality and accessible luxury while exploring the work of contemporary artists in America's only museum dedicated solely to art of the 21st Century. Whether you are visiting Bourbon Country, spending a day at Churchill Downs, or hosting a lavish Southern wedding, 21c is a modern epicenter for culture, activity, and artistic expression. Applauded by Travel & Leisure Magazine as "one of the most ambitious unions of art and hospitality ever undertaken," and hailed by The New York Times as "an innovative concept with strong execution and prompt and enthusiastic service," come meet the infamous Red Penguins and discover how 21c Museum Hotel is redefining the art of hospitality.

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Rock the Vote



A huge thanks to our fans who voted us 2009 #1 Hotel in the U.S. and #6 in the World!

We'd love your support again. Voting for the 2010 Readers' Choice Awards is open now.

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Celebrate National Ice Cream Month
with some House Made Italian Goodness


Proof on Main to donate a portion of
   July Gelato proceeds to charity