Welcome to the 21c Museum Hotel

21c Museum Hotel in Louisville, Kentucky is the first of its kind—a 90-room hotel dedicated to world-class luxuries, Southern-style hospitality and contemporary art from living artists. Nestled in the heart of Museum Row and downtown Louisville, 21c is an epicenter for culture, activity, and artistic expression. Whether you are visiting Bourbon Country, spending at day at Churchill Downs, or hosting a lavish Southern wedding, 21c has all the upscale offerings you'd expect from a boutique luxury hotel, yet offers so much more. Applauded by Travel & Leisure Magazine as "one of the most ambitious unions of art and hospitality ever undertaken," and hailed by The New York Times as "an innovative concept with strong execution and prompt and enthusiastic service," come meet the infamous Red Penguins and discover how 21c Museum Hotel is redefining the art of hospitality.